Rx only 30 Tablets SUN PHARMA, fluoxetine, quetiapine, lamotrigine, Seroquel, Prozac, Abilify, olanzapine, aripiprazole, risperidone, Depakote. Lithium a mood stabilizer that is a used to treat or control the manic episodes of bipolar disorder (manic depression ). Do not take Lithium carbonate tablets if you are allergic to Lithium or any of the ingredients in Lithium carbonate tablets. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. It works by decreasing abnormal activity in the brain. The safety and efficacy of Lithium as a treatment for acute manic or mixed episodes of bipolar I disorder in pediatric patients (ages 7 to ≤18 years) was demonstrated in an 8-week, randomized, placebo-controlled, parallel group study (NCT01166425). Advise pregnant women of the potential risk to a fetus. Indications, dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information for LITHIUM CARBONATE. Follow all directions on your prescription label and read all medication guides or instruction sheets. Inactive ingredients: microcrystalline cellulose, povidone, sodium lauryl sulfate, sodium starch glycolate type A, colloidal silicon dioxide and calcium stearate. EEG Changes: diffuse slowing, widening of frequency spectrum, potentiation and disorganization of background rhythm. Drink extra fluids to keep from getting dehydrated while you are taking this medication. PHARMACIST: Please dispense with Medication Guide provided separately to each patient. We have the Indications, Actions, Therapeutic Class, Pharmacologic Class and Nursing Considerations. Table 4: Clinically Important Drug Interactions with Lithium. Monitor neonates and provide supportive care until Lithium is excreted and toxic signs disappear, which may take up to 14 days. Generic Name: lithium (LITH ee um) Do not use Lithium carbonate tablets for a condition for which it was not prescribed. Reduce Lithium dosage based on serum Lithium concentration and clinical response. Symptoms include hypotonia, respiratory distress syndrome, cyanosis, lethargy, feeding difficulties, depressed neonatal reflexes, neonatal depression, apnea, and bradycardia. a MAO inhibitor - isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others. For more information about Lithium carbonate tablets, call 1-800-818-4555. Common signs include flaccid paralysis, dysarthria. Pregnancy, Advise pregnant women of the potential risk to a fetus and/or neonate [see Use in Specific Populations (8.1)]. Take your Lithium carbonate tablets exactly as prescribed by your healthcare provider. Lithium is not approved for use by anyone younger than 7 years old. The estimated plasma clearance was 0.59 L/h, 0.79 L/h and 1.17 L/h for pediatric patients weighing 20 kg, 30 kg and 50 kg, respectively. Prescription lithium (Eskalith, Lithobid) has been used for decades to treat some mental health conditions, including bipolar disorder depression. Lithium is used as a mood stabilizer, and is used for treatment of depression and mania. [see Boxed Warning, Dosage and Administration (, Common Adverse Reactions (incidence ≥ 5% and at least twice the rate of placebo), Adverse Reactions Occurring at an Incidence of 2% or More in Lithium-Treated Pediatric Patients. During treatment of hyponatremia, serum sodium should not be elevated by more than 10 to 12 mEq/L in 24 hours, or 18 mEq/L in 48 hours. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. 300 mg supplied as white to off-white, circular, biconvex, uncoated tablets debossed with “430” on one side and break line on other side. What are the ingredients in Lithium carbonate tablets? In the U.S. general population, the estimated background risk of major birth defects and miscarriage in clinically recognized pregnancies is 2 to 4% and 15 to 20%, respectively. Table 3: Adverse Reactions Reported in 2% or More of Pediatric Patients on Lithium and That Occurred at Greater Incidence Than in the Placebo Group in the 8-Week Acute Bipolar Trial. Get emergency medical help if you have signs of an allergic reaction to lithium: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Keep using the medication as directed and tell your doctor if your symptoms do not begin to improve after 1 week of treatment. Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Dec 2020), ASHP (updated 3 Dec 2020) and others. Facilities for prompt and accurate serum Lithium determinations should be available before initiating treatment, [see Dosage and Administration (2.3), Warnings and Precautions (5.1)]. If you faint or feel abnormal heartbeats, talk to your healthcare provider right away. How should I store Lithium carbonate tablets? Lithium toxicity that can cause death may happen even if the Lithium level in your blood is close to the right level for you. Lithium & Other Drugs Used in Treatment of Bipolar Disorder [BPD] or Bipolar Affective Disorder [BAD] If you need surgery, tell the surgeon ahead of time that you are using this medicine. If symptoms occur, decrease dosage or discontinue Lithium treatment. It is often used in bipolar disorder treatment. Lithium is in a class of medications called antimanic agents. For more severe hyponatremia (serum Na < 115 mEq/L), stupor, neuromuscular hyperexcitability, hyperreflexia, seizures, coma, and death can result. Too much lithium in your body can cause death. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. -Regular release formulations: 300 mg orally 3 to 4 times a day Avoid sodium restriction or diuretic administration. However, published studies in male mice and rats administered repeated daily dosing of Lithium carbonate report adverse effects on male reproductive organs, decreased spermatogenesis and decreased testosterone levels. Signs and symptoms of Lithium toxicity such as hypertonia, hypothermia, cyanosis, and ECG changes have been reported in some breastfed neonates and infants. Avoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids. Learn more about lithium (Eskalith, Lithobid), including a description, generic and brand names, drug class and mechanism, preparations, storage, reasons for prescription, dosing, drug interactions, and common side effects. The toxic concentrations for Lithium (≥1.5 mEq/L) are close to the therapeutic range (0.8 to 1.2mEq/L). Bottles of 30’s with Child Resistant Cap……………..NDC 62756-430-83 Talk to your healthcare provider about the best way to feed your baby if you take Lithium carbonate tablets. An encephalopathic syndrome, characterized by weakness, lethargy, fever, tremulousness and confusion, extrapyramidal symptoms, leukocytosis, elevated serum enzymes, BUN and fasting blood glucose, has occurred in patients treated with Lithium and an antipsychotic. Lithium-induced cases of hyperparathyroidism are more often multiglandular compared to standard cases. -Regular release formulations: 600 mg orally 3 times a day, in the morning, afternoon, and nighttime It is not known whether lithium will harm an unborn baby. Lithium carbonate can pass into your breastmilk and may harm your baby. Avoid becoming overheated or dehydrated during exercise and in hot weather. Store at room temperature away from moisture and heat. Early signs of toxicity include: vomiting, diarrhea, drowsiness, muscle weakness, or loss of coordination. Available for Android and iOS devices. Monitor for neurologic adverse reactions. dry mouth, increased thirst or urination; This is not a complete list of side effects and others may occur. Monitor patients for signs and symptoms of serotonin syndrome, particularly during Lithium initiation. If serotonin syndrome occurs, consider discontinuation of Lithium and/or concomitant serotonergic drugs, selective serotonin reuptake inhibitors (SSRI), serotonin and norepinephrine reuptake inhibitors (SNRI), monoamine oxidase inhibitors (MAOI). Who should not take Lithium carbonate tablets? Reports of neurotoxic reactions in patients treated with both Lithium and an antipsychotic, ranging from extrapyramidal symptoms to neuroleptic malignant syndrome, as well as reports of an encephalopathic syndrome in few patients treated with concomitant therapy, risperidone, haloperidol, thioridazine, fluphenazine, chlorpromazine, perphenazine, clozapine. Serotonin syndrome signs and symptoms may include mental status changes (e.g., agitation, hallucinations, delirium, and coma), autonomic instability (e.g., tachycardia, labile blood pressure, dizziness, diaphoresis, flushing, hyperthermia), neuromuscular symptoms (e.g., tremor, rigidity, myoclonus, hyperreflexia, incoordination), seizures, and gastrointestinal symptoms (e.g., nausea, vomiting, diarrhea). 259/15, Dadra-396 191, Drink extra fluids each day to prevent dehydration. Respiratory manifestations include dyspnea, aspiration pneumonia, and respiratory failure. See Table 2 for Lithium carbonate and Lithium oral solution dose conversion. Lithium is an element of the alkali-metal group with atomic number 3, atomic weight 6.94, and an emission line at 671 nm on the flame photometer. In rare cases, neurological sequelae may persist despite discontinuing Lithium treatment and may be associated with cerebellar atrophy. Manufactured by: Sodium affects excitation or mania. What is a proper diet to go on with lithium? Clinical Considerations Follow your doctor's instructions about the type and amount of liquids you should drink. For current information on the management of poisoning or overdosage, contact the National Poison Control Center at 1800-222-1222 or www.poison.org. Lithium Carbonate and Lithium Oral Solution Dose Conversion. It may take up to 3 weeks before your symptoms improve. Concomitant use can precipitate serotonin syndrome. People who take Lithium carbonate tablets may find out they also have a heart problem called Brugada Syndrome. Brugada Syndrome is a disorder characterized by abnormal electrocardiographic (ECG) findings and a risk of sudden death. Risk Summary In addition to regular monitoring of serum Lithium concentrations for patients on maintenance treatment, serum Lithium concentrations should be monitored after any change in dosage, concurrent medication (e.g., diuretics, non-steroidal anti- inflammatory drugs, renin-angiotensin system antagonists, or metronidazole), marked increase or decrease in routinely performed strenuous physical activity (such as an exercise program) and in the event of a concomitant disease [See Boxed Warning, Warnings and Precautions (5.1), Drug Interactions (7.1)]. Lithium (Eskalith ®, Eskalith CR ®, Lithobid ®) is a prescription drug approved for the treatment of bipolar disorder. It is also approved as a "maintenance treatment," which is a long-term treatment to help prevent episodes of mania or depression. This encephalopathic syndrome may be similar to or the same as neuroleptic malignant syndrome (NMS). After oral administration, Lithium is reported to be completely absorbed in the upper gastrointestinal tract. The biopsy findings in patients with Lithium induced CTIN include tubular atrophy, interstitial fibrosis, sclerotic glomeruli, tubular dilation, and nephron atrophy with cyst formation. selective serotonin reuptake inhibitors (SSRIs), serotonin norepinephrine reuptake inhibitors (SNRIs), medicines used to treat migraine headaches called triptans. Lithium toxicity can cause death. Concomitant use can lower serum Lithium concentrations by increasing urinary Lithium excretion. Lithium is not recommended for use in patients with severe renal impairment (creatinine clearance less than 30 mL/min evaluated by Cockcroft-Gault) [see Use in Specific Populations (8.6)]. Pressure inside the skull -severe headaches, ringing in your blood ( Lithium toxicity may occur the..., increased thirst or urination ; this is not complete and many other may. 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