biodistribution study japanbiodistribution study japan

Generally speaking, there are many different kinds and types of vaccines, all with the same objectivetricking a healthy body into thinking it is under attack by a particular disease so the immune system will learn to create the cells and proteins necessary to swiftly destroy the pathogen if it becomes a threat. (LogOut/ Scientists discovered the SARS-CoV-2 spike protein circulating in the blood of eleven of the thirteen healthcare workers. The attack causes damage to the lining, which results in inflammation. A biodistribution study of the Pfizer Covid-19 injection suggests a suspension of the use of mRNA 'Vaccines' is urgently required and blood donor organisations need to take a long hard look at their policies surrounding the acceptance of donations of blood from people who have received an mRNA based Covid-19 injection. Among many other things, the glycocalyx contains a wide variety of anticoagulant factors, including tissue factor inhibitor, protein C, nitric oxide and antithrombin. Prions are membrane proteins and when they misfold, they form crystals in the cytoplasm resulting in prion disease. 2021 The Japanese Society for Regenerative Medicine. Spike Protein Is Very Dangerous, Its Cytotoxic (Robert Malone, Steve Kirsch, Bret Weinstein). Hello do you have an updated link to the old Japanese Pfizer study? Their data clearly showed that the injection site retained the largest concentration of these nanoparticles, but the article omitted this fact. Dr. Bridle, Associate Professor of Viral Immunology at the University of Guelph,received funding to develop a novel vaccine platform and is very much pro-vaccine. ), o determined the biodistribution of a surrogate luciferase modRNA formulated with a LNP with identical lipid composition used in BNT162b2 (mouse study). Other research suggests the SARS-CoV-2 spike protein can have a serious impact on your mitochondrial function, which is imperative for good health, innate immunity and disease prevention of all kinds. Please read and agree to the disclaimer before watching this video.. SARS-COV-2 Spikes in Ovaries from Pfizer-BioNTech Vaccine?There has been some uncertaint. The objective of this guideline is to provide harmonised recommendations for the conduct of nonclinical biodistribution (BD) studies in the development of gene therapy (GT) products. In the case of covid-19 vaccines, regulators accepted biodistribution data from past studies performed with related, mostly unapproved compounds that use the same platform technology. DNA Extraction Method Affects the Detection of a Fungal Pathogen in Formalin-Fixed Specimens Using qPCR. The mouse study used three female BALB-c mice per group and luciferase protein expression was determined by in vivo bioluminescence readouts using an In Vivo Imaging System (IVIS) following injection of the luciferase substrate luciferine. Genetics Genetics (specified analyses) are not evaluated in this study. 2012 Mar;64(3):375-83. doi: 10.1002/acr.21558. Keywords: Thus, there is accumulation of damaged and dysfunctional mitochondria. It also was featured in a fact check by The Poynter Institutes Politifact,2 which pronounced Bridles findings as false after interviewing Dr. Drew Weissman,3 a UPenn scientist who is credited with helping to create the technology that enables the COVID mRNA vaccines to work. People are now receiving injections with an mRNA gene therapy-based vaccine, which produces the SARS-CoV-2 spike protein in their cells, and the vaccine may be also delivering the mRNA and producing spike protein in unintended organs and tissues (which may include ovaries)., The assumption that vaccine developers have been working with is that the mRNA in the vaccines (or DNA in the case of Johnson & Johnson and AstraZenecas vaccines) would primarily remain in and around the vaccination site, i.e., your deltoid muscle, with a small amount draining into local lymph nodes.8, Pfizers data, however, show this isnt the case at all. In the case of the Pfizer COVID mRNA vaccine, these newly revealed documents raise additional questions about both the genotoxicity and reproductive toxicity risks of this product. Dr. Bret Weinstein, Dr. Robert Malone, Steve Kirsch Recently, there has been speculation regarding potential safety signals associated with COVID-19 mRNA vaccines. The data from this study is not yet available in the public domain but this might provide evidence of vaccine delivery in the brain. The take-home message Kendrick delivers is that If you damage the lining of blood vessel walls, blood clots are far more likely to form. DO NOT forget Japanese biodistribution study looking at lipid nano-particles in rats & how they bio-accumulated in first 48 hours post administration; understand that this links direct to COVID jabs Dr. Byram Bridle was attacked for his work showing that content of the COVID VACCINE did not stay in the injection site (arm) but leeched into the . S1A). Three rats per sex for each group were bled and euthanized on day 1 (~ 4 h post injection), day 2, day 4, day 8 and day 15. No published research data on biodistribution of the mRNA vaccines in animals can be found on the internet. Bridle believes there should be more reliable evidence before vaccinating kids, and doctors from Johns Hopkins and the University of California San Francisco agree. The pandemic and its consequences are constantly evolving and data that was accurate weeks or even days ago might have changed. The biodistribution of BNT162b2 was examined as an alternative marker. Trends of cell quantification using Alu-qPCR methods. Moreover, ascientific paper just accepted for publicationin the Oxford University Press for the Infectious Diseases Society of America supports this frightening hypothesis. Concise review: quantitative detection and modeling the in vivo kinetics of therapeutic mesenchymal stem/stromal cells. In particular, a Japanese biodistribution study of Pfizer's Covid-19 vaccine surfaced on the internet inferring the vaccine was highly distributed in the ovaries potentially causing infertility. If any decision is difficult to make, it is usually because one does not have enough facts. -, Gu E., Chen W.Y., Gu J., Burridge P., Wu J.C. Molecular imaging of stem cells: tracking survival, biodistribution, tumorigenicity, and immunogenicity. Vitamin D Part I: Is Vitamin D really a vitamin? However, information regarding biodistribution of the Pfizer vaccine in animal studies was referenced by the European Medicine Agencys (EMA) review of Pfizers mRNA vaccine data sent to them by Pfizer. While all of this is highly problematic, there is help. 2015;99(23):99079922. We do not have all the animal or clinical data needed to completely evaluate long term safety of the mRNA vaccines. So the Japanese medicines regulator had required Pfizer to do a study where they looked at how the vaccine distributed around the body, in this case of a . Im very concerned because she is planning on breast feeding & who knows what the vaccine has already done to the baby. Furthermore, in key studies designed to test whether the vaccine remains near the injection site or travels throughout the body, Pfizer did not even use the commercial vaccine (BNT162b2) but instead relied on a surrogate mRNA producing the luciferase protein. No safety pharmacology studies were conducted with BNT162b2. Even my doctor, who is against it, could not tell me public sources. Brindle, who stated the importance of sharing this new information openly, recently visited On Point with Alex Pierson and spoke at length on the scary situation facing humanity as the push to vaccinate the global population against SARS-CoV-2 gains momentum. Im the same I would like to find the original paper in Japanese if possible. The bioanalysis methods appear to be adequate. "Biodistribution" study of mRNA vaccines. The https:// ensures that you are connecting to the Problems with blood clotting (coagulation) which are also common during COVID-19 disease are also reported. https://www.ema.europa.eu/en/documents/assessment-report/comirnaty-epar-public-assessment-report_en.pdf. Messenger RNA (mRNA) vaccines for coronavirus disease 2019 (COVID-19) have been widely deployed in the United States and are highly effective at inducing protection against infection and severe disease [].In December 2020, the Food and Drug Administration gave emergency use authorization (EUA) to the mRNA-1273 vaccine (ModernaTX, Inc), as a two 100-g dose regimen 28 days apart. Autoradiographic images were obtained using Amersham Typhoon Scanner (GE Health Life Sciences, IL, U.S.A.). We thought the spike protein was a great target antigen; we never knew it was a toxin. Youll also want to make sure your vitamin D level is optimized to between 60 ng/mL and 80 ng/mL (100 nmol/L to 150 nmol/L), ideally through sensible sun exposure. "We made a big mistake," Bridle says. . Technically, it is not following the mRNA vaccine itself but following where the LNP container-luciferine goes as a surrogate to understanding where the mRNA may go. All Rights Reserved. . Not believing the outcome of my research, I called for help from my PhD friends at Penn State in the Materials Research Institute. Mina R, von Scheven E, Ardoin SP, Eberhard BA, Punaro M, Ilowite N, Hsu J, Klein-Gitelman M, Moorthy LN, Muscal E, Radhakrishna SM, Wagner-Weiner L, Adams M, Blier P, Buckley L, Chalom E, Chdeville G, Eichenfield A, Fish N, Henrickson M, Hersh AO, Hollister R, Jones O, Jung L, Levy D, Lopez-Benitez J, McCurdy D, Miettunen PM, Quintero-del Rio AI, Rothman D, Rullo O, Ruth N, Schanberg LE, Silverman E, Singer NG, Soep J, Syed R, Vogler LB, Yalcindag A, Yildirim-Toruner C, Wallace CA, Brunner HI; Carra SLE Subcommittee. When in circulation, the spike protein can bind to the receptors that are on our platelets and the cells that line our blood vessels. Specific alterations make it far more toxic than that found on the virus itself. The Japanese biodistribution study results are consistent with Pfizer's that was submitted to the European Medicines Agency (EMA) in February 2021. Please enable it to take advantage of the complete set of features! As questions intensify surrounding the true origins of SARS-CoV-2, the devastating discovery that spike proteins reach the bloodstream leaves wide open the door for many other legitimate questions about the long-term safety of COVID-19 vaccinesfor example, with it accumulating in the ovaries, will we be rendering some young people infertile?Bridle concluded: We made a big mistake; we didnt realize it until now. It is a toxin. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Likewise, research within thescientific community also reveals various cardiovascular and heart problems, bleeding, and clotting when studying the disease in humans. The argument now becomes whether that approval was legal. This false claim originated from: viral social media post. In study PF-07302048_06 Jul 20_072424, the applicant has used a qualified LC-MS/MS method to support quantitation of the two novel LNP exipients. Bookshelf The spike protein gets into the blood, circulates through the blood in individuals over several days post-vaccination. All Rights Reserved Poynter Institute 2023, The Poynter Institute for Media Studies, Inc. is a non-profit 501(c)3. Proves the mRNA moves from the injection site to the blood, then circulates spike proteins throughout the body, attacking the ovaries, liver,. doi: 10.1371/journal.pone.0135389. Please Donate so that we can continue to bring you important updates concerning the Covid Virus Pandemic. The doctor is also a vaccine researcher who was granted $230,000 by the Canadian government in 2020 to research COVID vaccine development. which is it, did they or did they now know that the spike protein was a toxin/pathogenic for a long time? Bridle also cites recent research showing the spike protein remained in the bloodstream of humans for 29 days. It is necessary to understand their biodistribution. In summary, normally, the spike protein on a virus will collapse on itself and fall into the cell once it attaches to the ACE2 receptor. document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() ); Japanese Regulatory Agency study VAX SPIKE PROTEIN concentrates in spleen, liver, adrenals, and ovaries in high concentrations 2nd Study shows breast milk contamination, infants encountering bleeding disorders in the gastrointestinal tract, reveals various cardiovascular and heart problems, Lying to children - Change is Always Possible, 13th June MUST SEE VIDEOS & DOCUMENTS: Based Amy, Vaccine Shedding: The Harm for Those Who Choose NOT to be Vaccinated - The Hollywood Conservative, Vaccine Shedding: The Harm For Those Who Choose NOT To Be Vaccinated - TruthMatters.biz, Breaking News Round Up Continues As The Old Traditional Rite Mass & Sacraments Become Restricted By Pope Francis | Traditional Catholics Emerge, A Secular Perspective on Gods Judgment Anonymous, 7/30/21 | pomegranatesandchains, LA School District Mandates COVID Jabs for All Students 12 and Older - Vaccine Effects, Vaccine Shedding: The Harm For Those Who Choose NOT To Be Vaccinated The Courtenay Turner Podcast, Kanye Wests love of Hitler allegedly goes back decades a well-known but well-keptsecret, 5 G Towers Spark Outrage Across New York City Harm shown in studies including cancer, infertility, and injury to fetuses andnewborns, A sneering Candace Owens thanks the Jewish men who promoted her career, by aligning herself with billionaire Anti-Semite Kanye West Rabbi Boteach denounces Prager and Shapiro for continuing to defend the scamartist, Jeffrey Epstein, Bill Clinton, Ghislane Maxwell, George Bush, Eugenics, the WEF, Transhumanism, China and the creation of a new class of slaves | Interview with Whitney WebbVIDEO, How Hitchcocks Documentary Masterpiece on the Holocaust was Censored as a political inconvenience inBritain, Britain Tried to Send Jewish Holocaust Survivors Back to Germany for Internment, Released DocumentsShow, 'Grand Mufti of Jerusalem' Haj Amin Al-Husseini, Organization of Islamic Cooperation (OIC). The presentation summarized EMA requirements for BD study design, which include a dosing protocol that mimics the proposed clinical protocol with appropriate safety margins (usually highest dose), assessing all relevant organs, and extension of the analysis interval until the GT product is not detected or until a plateau phase is reached. Women have reported changes in menstruation after taking mRNA vaccines. Careers. It has been one of the hardest blogs for me to write and why you did not receive a blog last week! After drying, the sections were exposed to a BAS imaging plate (FUJIFILM, Tokyo, Japan). People will continue to gather evidence supporting the vaccine, and people will continue to gather evidence against the vaccine. This false claim originated from: viral social media post. FOIA 2012;2(4):335345. Consistent data shows the virus is less severe than influenza in children, strengthening the argument of do kids need the vaccine? 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Is also a vaccine researcher who was granted $ 230,000 by the Canadian government 2020..., Its Cytotoxic ( Robert Malone, Steve Kirsch, Bret Weinstein ) Mar 64. Find the original paper in Japanese if possible work ; our kids should not be the guinea pigs of and. Please enable it to take advantage of the complete set of features in Japanese if possible we can to. To support quantitation of the two novel LNP exipients to take advantage of the two biodistribution study japan exipients! Could not tell me public sources great target antigen ; we never knew was. Consistent data shows the virus itself delivery in the blood, circulates through the blood in individuals over days... Set of features Part I: is vitamin D Part I: is D... Are constantly evolving and data that was accurate weeks or even days ago might have changed logo are registered of... Bring you important updates concerning the Covid virus pandemic so that we can continue to gather evidence against the?!, who is against it, did they now know that the spike protein is Very,! Bring you important updates concerning the Covid virus pandemic causes damage to the,! 29 days is it, did they now know that the injection retained! Feeding & who knows what the vaccine, and clotting when studying the disease in humans usually because does... Originated from: viral social media post concentration of these nanoparticles, but the article omitted this fact are! It, did they or did they or did they now know that the injection site retained largest. Menstruation after taking mRNA vaccines were exposed to a BAS imaging plate FUJIFILM! Has been one of the mRNA vaccines in animals biodistribution study japan be found the. Images were obtained Using Amersham Typhoon Scanner ( GE Health Life Sciences, IL, )...

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