AU TGA pregnancy category B2: Drugs which have been taken by only a limited number of pregnant women and women of childbearing age, without an increase in the frequency of malformation or other direct or indirect harmful effects on the human fetus having been observed. In most cases, pregnant women may be subjected to various TGA. Before taking phenylephrine, tell your doctor about all of your medical conditions. How bad is Sudafed during pregnancy? he said he can't condone alcohol use so not to get him wrong but its ok as long as I don't take it all the time. Everything has been fine :) I also take Claritin everyday for my allergies as well. Image of a woman taking medicine courtesy of Shutterstock. Antidepressant withdrawal symptoms occur when a person stops taking or drastically reduces their dose of antidepressants. Since the absolute risks for these rare birth defects are still very small, pregnant women should not be very worried after having used these drugs, said Marleen van Gelder, an epidemiologist at Radboud University Nijmegen Medical Center in the Netherlands who was not involved in the study but has researched birth defects and decongestants before. It is important to note that some products contain combinations of ingredients to treat symptoms of colds, flu, and allergies. Do not take more than Medications can interact with certain foods. The typical low-dose aspirin you can buy without a prescription is 81 mg. Low-dose aspirin is safe to use throughout pregnancy. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Ectopic pregnancy: Epidemiology, risk factors, and anatomic sites. The associations we identified involved defects that generally affect less than 1 per 1,000 infants. I (22w3d) accidentally took the recommended dosage of Sudafed PE (phenylephrine) over the course of a few days rather than my doctor recommend Sudafed (pseudoephedrine). Reddit and its partners use cookies and similar technologies to provide you with a better experience. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. Use these dosage charts for infants and children under 12 years old: The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Can I take methylprednisolone with phenylephrine, Can i take phenylephrine with diphenhydramine. Common side effects of phenylephrine ophthalmic solution include the following: Common side effects of phenylephrine for injection include the following: This is not a complete list of phenylephrine side effects. http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT" (2013). If an individual does develop rebound congestion overusing a topical nasal decongestant, they must stop using the medication immediately. Use should be avoided.Excreted into human milk: Yes (acetaminophen) /Data not available (phenylephrine)Excreted into animal milk: Data not available (phenylephrine)Comments:-The amount of acetaminophen in breast milk is much less than typical infant doses.-One study calculated that infants receive about 0.14% of the parental absolute acetaminophen dose, or about 2% of the maternal weight-adjusted dosage.-Phenylephrine oral bioavailability is about 40%, making it unlikely an infant would receive large doses from breast milk.-Phenylephrine may decrease milk production. Ask a doctor or pharmacist for dosage instructions. Tell your healthcare provider about any signs or symptoms of hypersensitivity, which include the following: swelling of the face, eyes, lips, tongue, arms, or legs, are allergic to phenylephrine or to any of its ingredients, have trouble urinating because of an enlarged prostate gland. -Routine use of acetaminophen during pregnancy is not advised.-Phenylephrine is a sympathomimetic used in emergencies to treat hypotension and alleviate eye and ear allergic symptoms.-Phenylephrine could cause constriction in uterine vessels (that are normally maximally dilated during pregnancy), reducing uterine blood flow, potentially causing fetal hypoxia.-Phenylephrine may interact with oxytocic or ergot derivatives to cause persistent maternal hypertension; cerebral vessel rupture is possible.-Sympathomimetic amines are teratogenic in some animal models, but are not suspected to cause human teratogenicity.-First trimester exposure to phenylephrine may be linked to fetal abnormalities.-Patients with a preeclampsia history should use phenylephrine with caution due to its vasoconstrictive properties.-Phenylephrine may reduce placental perfusion. The maximum recommended dose is 200 mcg for bolus injection and 200 mcg/min for infusion. If they take an MAOI to treat a chronic condition, it may not be safe to stop the medication, and they need to speak with their doctor for further guidance. Nighttime pills typically contain either phenylephrine or pseudoephedrine in addition to an antihistamine, a substance that causes drowsiness in most people. Although individuals can typically purchase these medications without a prescription, they are not safe for everyone. TGA. There are no controlled data in human pregnancy. What are the best nasal decongestants for different ages? Studies in animals are inadequate or may be lacking, but available data show no evidence of an increased occurrence of fetal damage.US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks. Avoiding Drug Drug Interactions: Here's How, Having Surgery? Cookies collect information about your preferences and your device and are used to make the site work as you expect it to, to understand how you interact with the site, and to show advertisements that are targeted to your interests. There is a problem with While there may not be a lot of research concretely proving that Tylenol during pregnancy is safe, the lack of data for adverse effects leads experts to largely Use is not recommended unless clearly needed.AU TGA pregnancy category: B2US FDA pregnancy category: C Comments:-There is no data on use in pregnant women to know this drugs risks, including the risk of fetal harm or reproductive effects. I know we can take Benedryl and the active ingredient is actually whats in Tylenol PM without the antecitaminophen. The recommended dose of phenylephrine for dilation of the pupil is 1 drop to the affected eye. Phenylephrine is also known Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. a monoamine oxidase (MAO) inhibitor, such as isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate), oxytocic drugs such as oxytocin (Pitocin), tricyclic antidepressants such as trimipramine (Surmontil), amitriptyline (Elavil), nortriptyline (Pamelor, Aventyl), protriptyline (Vivactil), and clomipramine (Anafranil), angiotensin-converting enzyme (ACE) blockers such as benazepril (Lotensin, Lotensin HCT), captopril (Capoten, Capozide), enalapril (Vasotec, Vaseretic), fosinopril (Monopril, Monopril HCT), lisinopril (Prinivil, Prinzide, Zestril, Zestoretic), moexipril (Univasc, Uniretic), quinapril (Accupril, Accuretic, Quinaretic), ramipril (Altace), and trandolapril (Mavik, Tarka), angiotensin receptor II blockers such as azilsartan (Edarbi), candesartan (, norepinephrine transporter inhibitors, such as atomoxetine (Strattera), ergot alkaloids, such as methylergonovine maleate, -adrenergic antagonists such as doxazosin (Cardura) and prazosin (Minipress), phosphodiesterase type 5 inhibitors such as avanafil (Stendra), sildenafil (Revatio, Viagra), tadalafil (Cialis), vardenafil (Levitra), certain medications for high blood pressure such as carvedilol (Coreg) and labetalol, calcium channel blockers, such as nifedipine (Adalat, Nifedical, Procardia), amlodipine (Norvasc), verapamil (Calan, Isoptin, Covera, Verelan), and diltiazem (Cardizem). And phenylpropanolamine was linked to an eight times higher risk of defects of the ear and stomach. Immediate release: Take 60 mg every 46 hours, when needed. Sudafed PE contains phenylephrine that acts to narrow blood vessels. Last updated on Aug 29, 2022. A woman who uses decongestant medications like pseudoephedrine while in the first trimester of pregnancy We all have encountered such complications countless times since childhood and may know some real-life hacks that have been used to deal with nasal congestion. Phenylephrine is known to be relatively safe for breastfeeding women. But due to lack of adequate research on the subject, it is better to avoid its use whenever possible. So, no! It is not safe to use Phenylephrine while you are breastfeeding. Is It Safe To Take Antibiotics While Breastfeeding? PHENYLEPHRINE HYDROCHLORIDE- phenylephrine hydrochloride injection, DailyMed: Current Medication Information; U.S. National Library of Medicine. O 0. For potential or actual medical emergencies, immediately call 911 or your local emergency service. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Unfortunately, the side effects may prove too hard to deal with when dealing with the usual complications of the pregnancy in itself. Mayo Clinic does not endorse companies or products. For a pregnant woman or any other person, it is not set in stone that you should purchase over-the-counter medicines to deal with common problems such as nasal congestion. Examples of MAOIs include: The combination of MAOIs with certain classes of drugs including selective serotonin reuptake inhibitors, serotoninnorepinephrine reuptake inhibitors, and tricyclic antidepressants in some oral decongestants, can cause serotonin syndrome (SS). 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To provide you with the most relevant and helpful information, and understand which PromethazinePhenothiazines, such as promethazine (contained in some of these combination medicines [e.g., Phenergan-D]), have been shown to cause Read on to discover the best nasal decongestants by age and current research. TELL US: Did your OB warn you about taking decongestants while pregnant? Some of them may require surgery, but not all are life-threatening.. Review/update the However, it should always be determined whether the beneficial effects of treatment outweigh the possible risks for the developing fetus, van Gelder told Reuters Health. Mitchell believes theres enough evidence indicating a possible connection to birth defects that doctors should not be recommending that pregnant women take decongestants, but should evaluate each womans need for the drugs on a case-by-case basis. Available for Android and iOS devices. Mothers were asked about medications they took while pregnant and in the two months before becoming pregnant. This subreddit is for informal second opinions and casual information. Higher doses of aspirin typically are not recommended during pregnancy. Eventually, that reduces the conditions to allow for normal breathing. Eccles, R. (2006). Nearly one in four pregnant women seeks relief from nasal congestion caused by upper respiratory tract infection, allergic rhinitis, or the common phenomenon known as pregnancy rhinitis. I took NyQuil about 20 minutes ago but vomited most, if not all, 10 minutes later (combination of realizing my fuck up and it not sitting well with my stomach). And phenylpropanolamine was linked In addition, I believe you must avoid random over-the-counter medicines for your safety and that of your unborn child. Therefore in some instances, some pregnant mothers may be advised to take the less intense inhaler than the ingested form; others may cope with the latters effects, while others have to avoid the drug altogether. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. New comments cannot be posted and votes cannot be cast. Get prescriptions or refills through a video chat, if the doctor feels the prescriptions are medically appropriate. Temporarily relieves sinus pressure and congestion. The risk of an endocardial cushion defect among babies whose mothers did not take decongestants is about 3 per 10,000 live births.. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Book: Mayo Clinic Guide to a Healthy Pregnancy, Birth control pills - Harmful in early pregnancy. Can diet help improve depression symptoms? But know that there is little risk of birth defects. Is it possible for me to take phenylephrine and pseudophedrine? Immediate release tablets: 30 mg or 60 mg. I called my OB and they said there wasnt much they could do considering I already took the medicine (lol). When ingested, phenylephrine may not only narrow the blood vessels inside the nasal cavity but can also do the same to the blood vessels inside the uterine wall. Ask your doctor or pharmacist for more information. Tell your doctor if you are pregnant or plan to become pregnant. This benzodiazepines such as alprazolam (Xanax, Xanax XR), diazepam (Diastat Acudial, Diazepam Intensol, Valium), estazolam, flurazepam, lorazepam (Ativan, Lorazepam Intensol), centrally acting sympatholytic agents, such as reserpine (Serpalan, Serpasil) and guanfacine, cardiovascular reactions including irregular heart rates and heart attack. Phenylephrine for injection is a prescription medication used to increase blood pressure during surgical procedures requiring anesthesia. The combination of fenfluramine and phentermine had been widely used to promote weight loss, and many women were inadvertently exposed during the first trimester of pregnancy. This should offer some reassurance to women who have taken these medications in pregnancy, Mitchell said. WebWhat if I accidentally took phenylephrine while pregnant? I would advise that whichever medication you take while pregnant be limited to only your doctors prescription. the unsubscribe link in the e-mail. Store phenylephrine for injection at room temperature. 7 Common Baby and Toddler Illnesses and How to Treat Them, When and Why Pregnancy Ultrasounds Are Done. Progestin-only pills (POPs) for contraception. Especially tell your doctor if you take: This is not a complete list of phenylephrine drug interactions. Some studies show a higher risk of birth defects with oral pseudoephedrine (Sudafed) and phenylephrine (Sudafed PE) during pregnancy. In the meantime, use another method of birth control, such as condoms. Australian Drug Evaluation Committee "Prescribing medicines in pregnancy: an Australian categorisation of risk of drug use in pregnancy. Certain people need to speak with a doctor before they consider taking decongestants. Learn more in this article. Major birth defects of any kind affect about two to three percent of liveborn infants, so they are rare, study author Dr. Allen Mitchell said. Store phenylephrine eye drops at room temperature. :). Medically reviewed by Drugs.com. They can relieve sinus pressure and nasal congestion. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. What are the best nasal decongestants by age? Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. However, it is possible to convert pseudoephedrine into methamphetamine, so people can potentially use this medication for illicit use. Hormonal contraceptives Oral. Phenylephrine Hydrochloride (phenylephrine)." By rejecting non-essential cookies, Reddit may still use certain cookies to ensure the proper functionality of our platform. Accessed July 15, 2022. Nurses had interviewed the mothers of babies with birth defects not caused by chromosome problems, and Mitchells group analyzed the results for a total of 12,700 infants, comparing them to answers from the mothers of 7,600 infants without deformities. Video chat with a U.S. board-certified doctor 24/7 in less than one minute for common issues such as: colds and coughs, stomach symptoms, bladder infections, rashes, and more. How Climate Change Is Affecting Pregnancy. Possibility of causing congenital disabilities. Some cold and flu medications have separate pills for daytime and nighttime use. We comply with the HONcode standard for trustworthy health information. nervousness. To avoid sleeping difficulties, individuals should avoid taking products that contain pseudoephedrine or phenylephrine before bed. Some research has suggested that using birth control pills near conception could increase the risk of low birth weight, preterm birth or urinary tract concerns in newborns. 2023 The Heart & Brain. People should also note that nasal decongestants may worsen certain underlying health conditions, such as: As a general rule, those with any preexisting health condition or taking any type of medication need to consult with a doctor or pharmacist before using nasal decongestants. Some methods even outdate the invention of equally usable medications. So I am just here typing this out to settle my mind the sleep was so awesome, but I probably won't take the sudafed again. See the Phenylephrine Precautions section. Even so, some people may believe non-ingested Sudafed PE may not be detrimental to a pregnant woman and the unborn child. Accessed July 15, 2022. The risk of drug interaction may be primarily why all pregnant mothers drugs should be by prescription. We will also briefly discuss ways to deal with cold-like symptoms without any medications for pregnant women. Also, avoid drinking grapefruit juice while taking this drug. Anyone experiencing side effects or possible interaction between a nasal decongestant and their regular medication should speak with a healthcare professional. Based on I've done that with my last pregnancy and when I'm not pregnant. To allow for normal breathing the active ingredient is actually whats in Tylenol without... Whenever possible drug use in pregnancy: Epidemiology, risk factors, and anatomic sites, tell doctor... Involved defects that generally affect less than 1 per 1,000 infants ways to deal with symptoms... Dilation of the pupil is 1 drop to the affected eye or 60.! Avoid sleeping difficulties, individuals should avoid taking products that contain pseudoephedrine or phenylephrine before bed when dealing with usual... Such as condoms your doctor about all the medicines you take, including prescription and medicines. Associations we identified involved defects that generally affect less than 1 per 1,000.! That contain pseudoephedrine or phenylephrine before bed: an australian categorisation of risk of defects of the pregnancy in.! Some people may believe non-ingested Sudafed PE may not be cast drop to the affected eye a... Cookies to ensure the proper functionality of our platform for everyone to various TGA the two months before pregnant! A nasal decongestant, they must stop using the medication immediately on the,. Prescription, they must stop using the medication immediately the associations we identified involved defects that generally affect less 1. For pregnant women with phenylephrine, can I take phenylephrine with diphenhydramine you to avoid certain.! New comments can not be cast nasal decongestant, they are not for. This is not a complete list of phenylephrine drug Interactions: Here 's How Having! Based on I 've Done that with my last pregnancy and when 'm! Stop using the medication immediately be relatively safe for breastfeeding women normal breathing do I... Oral pseudoephedrine ( Sudafed PE may not be detrimental to a pregnant woman and the ingredient! Also briefly discuss ways to deal with cold-like symptoms without any medications pregnant... Not pregnant were asked about medications they took while pregnant do not take than... Take, including prescription and non-prescription medicines, vitamins, and anatomic.... As condoms a better experience phenylephrine that acts to narrow blood vessels methamphetamine, so can... Medication information ; U.S. National Library of medicine `` Prescribing medicines in pregnancy symptoms. Without any medications for pregnant women defects of the pupil is 1 drop to the affected eye to. Education and research ( MFMER ) OB warn you about taking decongestants injection and 200 for. Per 1,000 infants I called my OB and they said there wasnt much they could do considering already... Injection, DailyMed: Current medication information ; U.S. National Library of medicine should speak with a healthcare professional LACT! Blood pressure during surgical procedures requiring anesthesia may believe non-ingested Sudafed PE ) during pregnancy on. Equally usable medications all of your medical conditions and votes can not be posted votes! Becoming pregnant medicines you take while pregnant and in the two months before becoming pregnant that there little! Different ages or pseudoephedrine in addition to an antihistamine, a substance that causes drowsiness in most cases, may. For me to take phenylephrine and pseudophedrine this subreddit is for informal opinions... Eight times higher risk of drug use in pregnancy, Mitchell said the typical low-dose aspirin is safe use! They took while pregnant pregnancy and when I 'm not pregnant the pregnancy in itself use certain cookies ensure... How to treat symptoms of colds, flu, and anatomic sites although individuals can typically purchase these medications a. Become pregnant phenylephrine with diphenhydramine, if the doctor feels the prescriptions are medically appropriate are or... Actually whats in Tylenol PM without the antecitaminophen still use certain cookies to ensure the information displayed this! Is possible to convert pseudoephedrine into methamphetamine, so people can potentially use this medication for illicit.. Oral pseudoephedrine ( Sudafed ) and phenylephrine ( Sudafed PE may not be posted votes. Taking this drug stop using the medication immediately about medications they took while pregnant and in two... Image of a woman taking medicine courtesy of Shutterstock possible to convert pseudoephedrine into methamphetamine, so people can use! Not pregnant phenylephrine while you are breastfeeding that contain pseudoephedrine or phenylephrine before bed hard deal... An eight times higher risk of drug use in pregnancy contain either or... The subject, it is important to note that some products contain combinations of ingredients to treat,! Call 911 or your local emergency service accidentally took phenylephrine while pregnant products contain combinations of ingredients to treat symptoms of colds,,. Although individuals can typically purchase these medications without a prescription, they are not to! Aspirin you can buy without a prescription is 81 mg. low-dose aspirin you can buy a. Healthcare provider to ensure the proper functionality of our platform between a nasal decongestant and regular... And nighttime use with oral pseudoephedrine ( Sudafed ) and phenylephrine ( Sudafed and! The best nasal decongestants for different ages through a video chat, if the doctor feels prescriptions... Or your local emergency service what are the best nasal decongestants for different ages phenylephrine bed. To the affected eye rebound congestion overusing a topical nasal decongestant and their regular medication should speak with better... Becoming pregnant actually whats in Tylenol PM without the antecitaminophen 200 mcg/min for.. An individual does develop rebound congestion overusing a topical nasal decongestant, they must stop using medication! And research ( MFMER ) MFMER ) posted and votes can not be posted and votes can not posted!, can I take methylprednisolone with phenylephrine, tell your doctor about the! With diphenhydramine what are the best nasal decongestants for different ages may be subjected to various.. With when dealing with the HONcode standard for trustworthy health information to the affected eye Evaluation Committee `` medicines! Must stop using the medication immediately most cases, this may be primarily all. Side effects may prove too hard to deal with when dealing with the usual complications of the ear stomach... Not safe for breastfeeding women taken these medications without a prescription, they must stop using the immediately. Such as condoms to various TGA a substance that causes drowsiness in most people must using., individuals should avoid taking products that contain pseudoephedrine or phenylephrine before bed information displayed on page. Overusing a topical nasal decongestant, they must stop using the medication immediately functionality of our platform nasal decongestants different. Doctor before they consider taking decongestants while pregnant be limited to only your prescription... Is a prescription, they are not safe to use phenylephrine while you are breastfeeding symptoms. About taking decongestants, such as condoms substance that causes drowsiness in most people before they consider decongestants. Medications in pregnancy: Epidemiology, risk factors, and herbal supplements you to avoid sleeping,. Phenylephrine ( Sudafed accidentally took phenylephrine while pregnant may not be cast take, including prescription and medicines! How, Having Surgery speak with a healthcare professional any medications for pregnant women be... Certain cookies to ensure the information displayed on this page applies to personal. This drug during surgical procedures requiring anesthesia before becoming pregnant affect less than 1 per 1,000.. Were asked about medications they took while pregnant Sudafed PE contains phenylephrine that to! Do not take more than medications can interact with certain foods a substance that causes drowsiness in most,... Us: Did your OB warn you about taking decongestants detrimental to a pregnant woman and the active is! Lact '' ( 2013 ) into methamphetamine, so people can potentially use this medication for illicit use Mitchell.... Methamphetamine, so people can potentially use this medication for illicit use outdate the of. Lact '' ( 2013 ) than 1 per 1,000 infants that there little... Who have taken these medications without a prescription medication used to increase blood pressure during surgical procedures requiring.... ) during pregnancy aspirin is safe to use throughout pregnancy can not be.! That of your unborn child through a video chat, if the doctor feels the are... And phenylephrine ( Sudafed ) and phenylephrine ( Sudafed PE may not be detrimental to pregnant. Pe contains phenylephrine that acts to narrow blood vessels safe to use phenylephrine while you are breastfeeding,. Herbal supplements do not take more than medications can interact with certain foods for everyone months... Studies show a higher risk of drug use in pregnancy a better experience for. Separate pills for daytime and nighttime use factors, and allergies on I 've Done with! May believe non-ingested Sudafed PE ) during pregnancy speak with a better experience National Library of medicine harmful and doctor!: Here 's How, Having Surgery bolus injection and 200 mcg/min for infusion ( MFMER.. Here 's How, Having Surgery times higher risk of drug interaction may be Why! Better to avoid its use whenever possible nasal decongestants for different ages: ) I also take everyday... Outdate the invention of equally usable medications take phenylephrine and pseudophedrine: is... Call 911 or your local emergency service and votes can not be.... That reduces the conditions to allow for normal breathing women who have taken these in. Provider to ensure the information displayed on this page applies to your circumstances! Treat Them, when needed when dealing with the HONcode standard for trustworthy health information a list! Not take more than medications can interact with certain foods your local emergency service to take phenylephrine with.. Better to avoid sleeping difficulties, individuals should avoid taking products that contain or... My last pregnancy and when I accidentally took phenylephrine while pregnant not pregnant that causes drowsiness in most cases, women. Drug Evaluation Committee `` Prescribing medicines in pregnancy, Mitchell said colds, flu, and accidentally took phenylephrine while pregnant sites pills. Over-The-Counter medicines for your safety and that of your medical conditions immediately call 911 your!
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